• Course

2 hours

All audiences

Anticoagulants: show me the evidence!

After completing this course, you should be able to:

  • Explain the complications of anticoagulation therapy
  • Review the differences in pharmacokinetics, efficacy, and safety between newer anticoagulant drugs and warfarin
  • Apply the important patient counselling points.

About this course

Optimal oral anticoagulant therapy requires careful consideration of patient's needs and an understanding of the efficacy, safety, pharmacokinetics of the anticoagulants, and the methods used to measure their effects. Warfarin, a vitamin K antagonist, has been the mainstay of oral anticoagulation therapy for over several decades. However, warfarin is associated with a number of difficulties, including the need for constant INR monitoring, dosing adjustments, dietary restrictions, and clinically significant drug interactions.

Finding an alternative to warfarin has been a focus of recent research. The newer oral anticoagulants that inhibit factor IIa or factor Xa have more predictable pharmacokinetics, fewer drug and diet interactions, and no need for routine laboratory monitoring and dose adjustments. Adherence is especially important with these new anticoagulants because they have relatively short half lives. The pharmacist has a significant role in keeping updated with these new anticoagulant drugs, educating patients about their drugs, and the importance of adhering to their anticoagulant therapy.

You will be invited to complete a survey at the end of the course to claim your ACPE certificate.


Sotiris Antoniou, Craig Coleman, Filipa Alves da Costa, Helen Williams....


Accreditor credit Accreditation statement
BMJ and EAHP 0.15 credits, 2:00 hours This course is accredited to the combined value of the modules it contains. (Universal Activity Number (UAN): 0475-0000-20-031-H04-P)

Release date

22 Dec 2017