Angiotensin receptor blockers and risk of myocardial infarction: meta-analyses and trial sequential analyses of 147 020 patients from randomised trials
The purpose of this activity is to evaluate reports of increased risk of myocardial infarction with the use of angiotensin receptor blockers (ARBs) and to evaluate the utility of angiotensin receptor blockers at reducing the risk of other cardiovascular outcomes.
1) Identify the association between use of angiotensin receptor blockers and risk of myocardial infarction
2) Identify the role of angiotensin receptor blockers in reducing the risk of other cardiovascular outcomes and other outcomes in patients with cardiovascular conditions
3) Appraise the study design and the strength of evidence for these associations
4) Recognise the potential implications of the findings for public health.
William D Carey, MD and Dr Kirsten Patrick
William D Carey, MD and Dr Kirsten Patrick
William D Carey, MD is Director, Center for Continuing Education, Cleveland Clinic, Cleveland, Ohio. Dr Kirsten Patrick is an Assistant Editor, British Medical Journal, London.
We declare no financial interests, commercial affiliations, or conflicts of interest.
CME Disclaimer :
The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by any of the accreditors. In no event will any of the accreditors be liable for any decision made or action taken in reliance upon the information provided through this CME activity.
19 Apr 2011
19 Apr 2011
19 Apr 2012
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